` The Metabolomics Publications
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Project 3 Publications

Representative Recent Publications

Pannkuk EL, Fronace Jr AJ, Laiakis EC. Metabolomic Applications in Radiation Biodosimetry: Exploring Radiation Effects Through Small Molecules Int J Radiat Biol 2017 [Epub ahead of print] [abstract]

Laiakis EC, Strawn SJ, Brenner DJ, Fornace Jr AJ. Assessment of saliva as a potential biofluid for biodosimetry: a pilot metabolomics study in mice. Radiat Res 2016 186(1):92-97 [abstract] [full text]

Goudarzi M, Chauthe S, Strawn SJ, Weber WM, Brenner DJ, Fornace Jr AJ. Quantitative Metabolomic Analysis of Urinary Citrulline and Calcitroic Acid in Mice after Exposure to Various Types of Ionizing Radiation. Int. J. Mol. Sci. 2016, 17(5), 782. [abstract] [full text]

Goudarzi M, Weber WM, Chung J, Doyle-Eisele M, Melo DR, Mak TD, Strawn SJ, Brenner DJ, Guilmette R, Fornace AJ Jr. Serum Dyslipidemia Is Induced by Internal Exposure to Strontium-90 in Mice, Lipidomic Profiling Using a Data-Independent Liquid Chromatography-Mass Spectrometry Approach J Proteome Res 2015 Sep 4;14(9):4039-49. [abstract] [full text]

Goudarzi M, Weber WM, Mak TD, Chung J, Doyle-Eisele M, Melo DR, Strawn SJ, Brenner DJ, Guilmette RA, Fornace AJ. A Comprehensive Metabolomic Investigation in Urine of Mice Exposed to Strontium-90. Radiat Res 2015; 183: 665-674. [abstract]

Goudarzi M, Weber WM, Chung J, Doyle-Eisele M, Melo DR, Mak TD, Strawn SJ, Brenner DJ, Guilmette RA, Fornace AJ. Serum Dyslipidemia Is Induced by Internal Exposure to Strontium-90 in Mice, Lipidomic Profiling Using a Data-Independent Liquid Chromatography-Mass Spectrometry Approach. J Proteome Res 2015; 14:4039-4049. [abstract]

Laiakis EC, Pannkuk EL, Diaz-Rubio ME, Wang YW, Mak TD, Simbulan-Rosenthal CM, Brenner DJ, Fornace AJ. Implications of genotypic differences in the generation of a urinary metabolomics radiation signature. Mutat Res 2016. [abstract]

Mak TD, Laiakis EC, Goudarzi M, Fornace AJ. Selective paired ion contrast analysis: a novel algorithm for analyzing postprocessed LC-MS metabolomics data possessing high experimental noise. Anal Chem 2015; 87:3177-3186. [abstract] [full text]

Mak TD, Tyburski JB, Krausz KW, Kalinich, JF, Gonzalez FJ, and Fornace AJ. Exposure to ionizing radiation reveals global dose- and time-dependent changes in the urinary metabolome of rat. Metabolomics 2015; 11:1082-1094. [abstract]

Goudarzi M, Weber WM, Mak TD, Chung J., Doyle-Eisele M, Melo DR, Brenner DJ, Guilmette RA, and Fornace AJ.Metabolomic and lipidomic analysis of serum from mice exposed to an internal emitter, Cesium-137, using a shotgun LC-MS approach. J Proteome Res 2015; 14: 374-384. [abstract] [full text]

Hyduke DR, Laiakis EC, Li HH, and Fornace AJ.Identifying radiation exposure biomarkers from mouse blood transcriptome. Int J Bioinform Res Appl 9: 365-385, 2013. PMCID: PMC4180524[abstract] [full article]

Laiakis EC, Strassburg K, Bogumil R, Lai S, Vreeken RJ, Hankemeier T, Langridge J, Plumb RS, Fornace AJ Jr, Astarita G. Metabolic Phenotyping Reveals a Lipid Mediator Response to Ionizing Radiation. J Proteome Res. 2014 Sep 5;13(9):4143-54. PMCID: PMC4156265.[abstract] [full text]

Goudarzi M, Mak TD, Chen C, Smilenov LB, Brenner DJ, Fornace AJ.The effect of low dose rate on metabolomic response to radiation in mice. Radiat Environ Biophys. 2014 Nov;53(4):645-57. PMCID: PMC4206600 [abstract] [full text]

Goudarzi M, Weber W, Mak TD, Chung J, Doyle-Eisele M, Melo D, Brenner DJ, Guilmette RA, Fornace AJ.Development of urinary biomarkers for internal exposure by cesium-137 using a metabolomics approach in mice. Radiat Res. 2014 Jan;181(1):54-64. PMCID: PMC4029349[abstract] [full text]

Mak TD, Laiakis EC, Goudarzi M, Fornace AJ. JrMetaboLyzer: a novel statistical workflow for analyzing Postprocessed LC-MS metabolomics data. Anal Chem. 2014 Jan 7;86(1):506-13. doi: 10.1021/ac402477z. Epub 2013 Nov 22. [abstract] [full text]

Hyduke DR, Laiakis EC, Li HH, Fornace AJ Jr.Identifying radiation exposure biomarkers from mouse blood transcriptome. Int J Bioinform Res Appl. 2013;9(4):365-85. doi: 10.1504/IJBRA.2013.054701.[abstract] [full text]

Evagelia C Laiakis, Albert J Fornace Jr, Ralf Bogumil, Cornelia Roehring, Michael Daxboeck, Marc Bret, Steven Lai, John Shockcor, Steven Cohen, James Langridge, Giuseppe Astarita. Targeted Metabolomics Using the UPLC/MS-based AbsoluteIDQ p180 Kit. Waters Corporation, Application Note.[full text]

Laiakis EC, Mak TD, Anizan S, Amundson SA, Barker CA, Wolden SL, Brenner DJ, Fornace AJ Jr. Development of a metabolomic radiation signature in urine from patients undergoing Total Body Irradiation. Radiat Res. 2014 Apr;181(4):350-61. PMCID: PMC4071158[abstract] [full text]

Laiakis EC, Hyduke DR, Fornace AJ.Comparison of mouse urinary metabolic profiles after exposure to the inflammatory stressors γ radiation and lipopolysaccharide. Radiat Res. 2012 Feb;177(2):187-99. PMCID:PMC3286010[abstract] [full text]

Coy SL, Cheema AK, Tyburski JB, Laiakis EC, Collins SP, Fornace A Jr. Radiation metabolomics and its potential in biodosimetry. Int J Radiat Biol. 2011 Aug;87(8):802-23. PMCID: PMC3572797[abstract] [full text]

 

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